There is no known increased risk of abnormality in babies born as a result of IVF procedures. There are some risks associated with IVF therapies.
The symptoms are abdominal swelling or bloating because of enlarged ovaries, nausea and, as the condition gets worse, vomiting.
Fertility drugs stimulate the ovaries to produce many egg sacs (follicles). Sometimes there is an excessive response to fertility drugs and this causes OHSS. Overstimulated ovaries enlarge and release chemicals into the bloodstream that make blood vessels leak fluid into the body. Fluid leaks into your abdomen and, in severe cases, into the space around the heart and lungs. OHSS can affect the kidneys, liver, and lungs. A serious, but rare, complication is a blood clot (thrombosis). A very small number of deaths have been reported world wide.
Mild symptoms are common in women having IVF treatment. As many as one in three (33%) women develop mild OHSS. About one in 20 (5%) women develop moderate or severe OHSS.
The risk of OHSS in increased in women who:
With spontaneous conceptions, a little more than 1% of pregnancies will be multiples (twins, triplets, or more). This rate is significantly increased with in-vitro fertilization (IVF), so that in Canada the risk of a twin pregnancy is approximately 30% and that of triplets or more is approximately 2% with IVF. Risks increase with the number of embryos transferred to the uterus in IVF. For a couple dealing with the anguish of infertility, a multiple pregnancy may appear to be a good outcome. However, there are a number of serious complications associated with multiple pregnancy that make it considerably less desirable than a single fetus pregnancy.Many of the complications of pregnancy that a mother may experience (high blood pressure, bleeding, diabetes) are increased. The number of physician visits, ultrasound examinations, and days in hospital are far more with a twin or triplet pregnancy. The frequency of Cesarean Section is in the range of 50% with a twin pregnancy, and is advised in virtually all triplet or higher pregnancies.
By far, the most serious issue is that of achieving the goal of a live-born, healthy child. The biggest concern with multiple pregnancy is the risk of pre-term birth. Twins are born on average five weeks prior to term, triplets eight weeks prior to term, and quadruplets or higher more than ten weeks prior to term. A great majority of pre-term twin and virtually all triplets and quadruplets spend periods of time (sometimes prolonged) in newborn intensive care. There is the need for ventilator or respirator care, and complications such as brain hemorrhage, leading to increased risks of developmental delay and cerebral palsy. Chronic long-term respiratory difficulties, visual impairment, and bowel disorders are greatly increased with pre-term birth. The risk of death and cerebral palsy is up to five times greater for a twin newborn and more than ten times greater for a triplet newborn than for a single birth.
These realities are why care providers encourage careful consideration of the number of embryos transferred, so as to reduce the risk of multiple pregnancy while achieving ideal live birth success rates.
The AART team will review your therapies whether or not pregnancy occurs after treatment. A physician will meet with you after the review has taken place to discuss the cycle and to recommend adjustments should another cycle be undertaken.